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Scientific Collaborations
   
  InSight is continuously engaged in Heparanase-related research collaborations with numerous leading research groups and institutions.

 
               
  Researcher Institution Collaboration title Related scientific publications
         
  I Vlodavsky Department of Oncology,
Hadassah-Hebrew
University Hospital, Jerusalem
1. Heparanase cloning
   
2. Heparanase role in angiogenesis
   
3. Heparanase expression in solid and hematopoietic tumors
   
4. Heparanase localization and activation
   
5. Heparanase role in wound healing
   
Nat Med. 1999 Jul;5(7): 793-802
   
FASEB J. 2001 Jul;15(9): 1661-3
   
Am J Pathol. 2000 Oct; 157(4):1167-75.
   
Exp Hematol. 2002 Jan; 30(1):34-41.
   
J Cell Sci. 2002 May 15; 115(Pt 10):2179-87
   
J Mammary Gland Biol Neoplasia. 2001 Jul; 6(3):311-22
   
J Biol Chem. 2001 Aug 3; 276(31):29178-87
   
         
  A Eldor, BZ Katz Department of Hematology, Tel-Aviv Sourasky Medical Center, Tel-Aviv Heparanase localization and activation
Exp Cell Res. 2002 Nov 15;281(1):50-62
   
J Cell Sci. 2002 May 15;115(Pt 10):2179-87
   
         
  T Brener Department of Neurology, Hadassah-Hebrew University Hospital, Jerusalem A synthetic heparin-mimicking polyanionic compound inhibits central nervous system inflammation
J Neurol Sci. 2003 Jan 15;206(1):49-57.
         
         
  A Nagler Bone Marrow Transplantation Department and Cord Blood Bank, The Chaim Sheba Medical Center, Tel-Hashomer, Israel Study of heparanase expression in normal and leukemic hematopoiesis;The effect of heparanase on cell transplantation into an injured tissue  
         
         
  U Lindahl Department of Medical Biochemistry and Microbiology, University of Uppsala, Sweden Processing of macromolecular heparin by heparanase
J. Biol. Chem. (July 1, 2003)
         
         
  mw Buchler; H Friess;J Kleef; M Wirtz Department of Visceral and Transplantation Surgery, University of Bern, Switzerland and Department of General Surgery, University of Heidelberg, Germany
1. Heparanase Expression in Primary and Metastatic Pancreatic Cancer
   
2. Heparanase expression in hepatocellular carcinoma and the cirrhotic liver
   
3. Heparanase expression in pancreatic cancer - initiated 2003
   
Cancer Research 61: 4655-4659 (2001)
   
Hepatology Research 26: 192-198 (2003)
   
         
  K Caca Department of Medicine II, Leipzig University,Germany Heparanase is a prognostic indicator postoperative survival in pancreatic carcinoma
Br. J. Cancer 86:1270-1275 (2002);
   
Br. J. Cancer 87:689 (2002)
   
         
  G Jenniskense Department of Biochemistry, University of Nijmegen, The Netherlands Heparanase role in skeletal muscle physiology
The FASEB J. 17: 878-880 (2003)
         
         
  J van den Berg Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands Minimal change nephrotic syndrome is associated with increased glomerular expression of heparanase
Submitted to Kidney International
         
         
  M Yamamoto Department of Neurosurgery,Fukuoka University School of Medicine, Fukuoka,Japan The role of heparanase in glioblastoma  
         
         
  Q Xueshan Department of Pathology, Cina Medical University, Shenyang, Liaoning, China Heparanase role in lung cancer invasion and metastasis
China Lung Cancer Magazine, September 2003
         
         
  CA Stein Department of Medicine, Columbia University, NY, USA Antisense knockout of heparanase in cancer and metastasis  
         
         
  I Bab Institute of Dental Sciences, Faculty of Dental Medicine, The Hebrew University of Jerusalem, Israel The effect of heparanase on bone regeneration  
         
         
  A Solomon, A Grinbaum Maurice and Gabriela Goldshlager Eye Research Institute, Sakler Faculty of Medicine, Chaim Sheba Medical Center, Tel-Hashomer, Israel Heparanase-mediated corneal healing  
         
         
  V Schirrmacher Division of Cellular Immunology,German Cancer research Center (DKFZ), Germany The role of heparanase in cancer  
         
         
  RA Sobel Veterans AffairsHealthcare System, Palo alto, CA, USA Extracellular matrix and the failure of repair in Chronic MS lesions  
         
   
 
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